Recombinant Human Calumenin Protein (aa 1-311, His Tag)
Product Specifications
Background
Calumenin belongs to the CREC family. It contains 6 EF-hand domains. Calumenin is expressed in skeletal muscle (at protein level) . Calumenin interacts with GGCX and RYR1 in the presence of calcium ions; but not in the presence of EDTA. Calumenin is Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. It seems to inhibit gamma-carboxylase GGCX. Calumenin also binds 7 calcium ions with a low affinity and may modulate calcium release from the sarcoplasmic reticulum.
Synonyms
CALU; Calumenin; Crocalbin; IEF SSP 9302
UniProt
O43852
Accession Number
O43852-1
Expression System
HEK293 Cells
Tag
C-His
Sequence
Met 1-Arg311
Field of Research
Tags & Cell Markers, Signal Transduction
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/lu1typ
Product MSDS
https://789.bio/eb/zjHmv5
Calculated Molecular Weight
35.9 kDa
Observed Molecular Weight
46-52 kDa
Species
Human
Curated Selection
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