IRF5-CPP5
IRF5-CPP5 is a cytosolic peptide that selectively inhibits human IRF5 with IC50 values of 15.4 and 15.3 μM for recombinant S430D or wild-type (WT) IRF5 dimerization, respectively.[1].
Product Specifications
CAS Number
1601299-92-6
UNSPSC
12352209
Target
Toll-like Receptor (TLR)
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Purity
95.38
Smiles
O=C(NC(C)C(NC(CC(N)=O)C(NC(CC(C)C)C(NCC(NC(CC1=CC=C(C=C1)O)C(NC(CC2=CNC3=CC=CC=C23)C(NC(CC(C)C)C(NC(CC(C)C)C(NC(C)C(NC(CC(C)C)C(NC(CC4=CC=CC=C4)C(NC(C(C)C)C(NC(C(O)C)C(NC(CC5=CC=C(C=C5)O)C(NC(CC6=CNC7=CC=CC=C67)C(NC(C(O)C)C(NC(CC(O)=O)C(NC(CC(C)C)C(NCC(NC(CC(C)C)C(NC(C(C)C)C(NC(CCCCN)C(NC(CCCCN)C(NC(CCCNC(N)=N)C(N8C(CCC8)C(NC(CCCCN)C(N9[C@H](CCC9)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(CCSC)N
Molecular Formula
C160H245N37O36S
Molecular Weight
3294.95
References & Citations
[1]Banga J, et al. Inhibition of IRF5 cellular activity with cell-penetrating peptides that target homodimerization. Sci Adv. 2020 May 15;6 (20) :eaay1057.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
A16820-10mM-D 10 mM x 1mL in DMSO
AZD-4635 (HTL1071) 10mM * 1mL in DMSO
Sign In for Pricing
View Details 