L57 (acetate)
L57 acetate is a Low-density lipoprotein receptor-related protein 1 (LRP1) -binding peptide. L57 acetate exhibits high affinity to LRP1 with Ki of 45 nM. L57 acetate exhibits blood-brain barrier (BBB) permeability and plasma stability. L57 acetate can be utilized as the carrier for CNS drug delivery[1].
Product Specifications
UNSPSC
12352209
Target
LDLR
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Purity
99.01
Smiles
O=C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N3[C@@H](CCC3)C(N[C@@H](CCCCN)C(N[C@@H](CC4=CNC=N4)C(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC6=CNC=N6)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC7=CC=CC=C7)C(N[C@@H](CC8=CC=C(C=C8)O)C(N[C@@H](CO)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CCCCN)C(N[C@@H](CC9=CNC=N9)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@H](O)C)N.CC(O)=O.[x]
Molecular Formula
C120H175N31O27.xC2H4O2
Molecular Weight
2483.87 (free base)
References & Citations
[1]Sakamoto K, et al., A novel LRP1-binding peptide L57 that crosses the blood brain barrier. Biochem Biophys Rep. 2017 Aug 12;12:135-139.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LC431170 20 µg
ST6GALNAC3 (NM_001160011) Human Over-expression Lysate
Sign In for Pricing
View Details 
