4H-Tomentosin
4H-Tomentosin is a mixed-competitive type soluble epoxide hydrolase (sEH) inhibitor with an IC50 of 6.84 μM and a Ki of 7.02 μM. 4H-Tomentosin interacts with sEH by forming hydrogen bonds with Tyr343, Ile363, and Tyr383[1].
Product Specifications
CAS Number
[68776-19-2]
UNSPSC
12352005
Target
Epoxide Hydrolase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Smiles
O=C1OC2CC(C)C(CCC(C)O)=CCC2C1=C
Molecular Formula
C15H22O3
Molecular Weight
250.33
References & Citations
[1]He X, et al. Natural soluble epoxide hydrolase inhibitors from Inula helenium and their interactions with soluble epoxide hydrolase. Int J Biol Macromol. 2020 Apr 29:S0141-8130 (20) 33090-7.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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