Oleracone
Oleracone is a type of alkaloid that can be found in Portulaca oleracea L.. Oleracone exhibits a significant anti-inflammatory effect in the RAW 264.7 macrophage model induced by LPS , capable of inhibiting NO production and significantly suppressing the secretion of pro-inflammatory cytokines TNF-α, IL-6, and prostaglandin E₂ (PGE₂). Oleracone can be used for the study of inflammatory diseases[1].
Product Specifications
CAS Number
1863920-09-5
UNSPSC
12352005
Target
Interleukin Related; NO Synthase; TNF Receptor
Related Pathways
Apoptosis; Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
O=C1C=C(C(C)=CC2=C1NC(C)(C2)C)C(C)=O
Molecular Formula
C14H17NO2
Molecular Weight
231.29
References & Citations
[1]Meng Y, et al. The anti-inflammation and pharmacokinetics of a novel alkaloid from Portulaca oleracea L. J Pharm Pharmacol. 2016 Mar;68 (3) :397-405.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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