Oleracone

Oleracone is a type of alkaloid that can be found in Portulaca oleracea L.. Oleracone exhibits a significant anti-inflammatory effect in the RAW 264.7 macrophage model induced by LPS (HY-D1056), capable of inhibiting NO production and significantly suppressing the secretion of pro-inflammatory cytokines TNF-α, IL-6, and prostaglandin E₂ (PGE₂) . Oleracone can be used for the study of inflammatory diseases[1].

Product Specifications

CAS Number

[1863920-09-5]

UNSPSC

12352005

Target

Interleukin Related; NO Synthase; TNF Receptor

Related Pathways

Apoptosis; Immunology/Inflammation

Field of Research

Inflammation/Immunology

Smiles

O=C1C=C(C(C)=CC2=C1NC(C)(C2)C)C(C)=O

Molecular Formula

C14H17NO2

Molecular Weight

231.29

References & Citations

[1]Meng Y, et al. The anti-inflammation and pharmacokinetics of a novel alkaloid from Portulaca oleracea L. J Pharm Pharmacol. 2016 Mar;68 (3) :397-405.