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Antiproliferative agent-69

Antiproliferative agent-69 (Compound 1) is a prenylated kaempferol derivative found in the fresh bud’s fur of Platanus acerifolia. Antiproliferative agent-69 shows significant antiproliferative effects against human breast cancer cells (MCF-7) and human hepatocellular carcinoma cells (Hep-G2) with IC50 values of 38.2 μM and 39.5 μM, respectively. Antiproliferative agent-69 is promising for research of breast cancer and liver cancer[1].

Product Specifications

CAS Number

[1859979-00-2]

UNSPSC

12352005

Target

Drug Derivative

Related Pathways

Others

Field of Research

Cancer

Smiles

O=C1C(O)=C(C2=CC(OC)=C(O)C=C2)OC3=C(C(C)(C)C=C)C(O)=CC(O)=C31

Molecular Formula

C21H20O7

Molecular Weight

384.38

References & Citations

[1]Zuo B, et al. Two novel prenylated kaempferol derivatives from fresh bud's fur of Platanus acerifolia and their anti-proliferative activities. Nat Prod Res. 2016 Nov;30 (22) :2523-2528.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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