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5-N-Acetylardeemin

5-N-Acetylardeemin potentiated the cytotoxicity of the anticancer agent Vinblastine (HY-13780) in multidrug resistant human tumor cells[1].

Product Specifications

CAS Number

[148441-26-3]

UNSPSC

12352005

Target

Others

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

C=CC(C)([C@]12[C@](N(C3=CC=CC=C32)C(C)=O)([H])N4[C@@](C(N5[C@@H](C4=O)C)=NC6=CC=CC=C6C5=O)([H])C1)C

Molecular Formula

C28H28N4O3

Molecular Weight

468.55

References & Citations

[1]Daigo Hayashi, et al. Synthesis and ABCG2 inhibitory evaluation of 5-N-acetylardeemin derivatives. Bioorg Med Chem. 2015 May 1;23 (9) :2010-23.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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