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[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide

Product Specifications

UNSPSC Description

[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide is a potent and selective neuropeptide Y Y5 receptor agonist with an IC50 of 0.24 nM for binding to the hY5 receptor. [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide induces a high amount of food intake[1].

Target Antigen

Neuropeptide Y Receptor

Type

Peptides

Related Pathways

GPCR/G Protein;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cpp1-7-npy19-23-ala31-aib32-gln34-hpancreatic-polypeptide.html

Purity

99.25

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(N1[C@@H](CCC1)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N2[C@@H](CCC2)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC3=CC=C(C=C3)O)C(N4[C@@H](CCC4)C(NCC(N[C@@H](CC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](C)C(N[C@@H]([C@H](O)C)C(N5[C@@H](CCC5)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCSC)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC6=CC=C(C=C6)O)C(N[C@@H](CC7=CC=C(C=C7)O)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC8=CC=C(C=C8)O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(N)=O)C(N[C@@H](CCSC)C(N[C@@H](C)C(NC(C)(C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC9=CC=C(C=C9)O)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CN

Molecular Weight

4207.66

References & Citations

[1]C Cabrele , et al. The first selective agonist for the neuropeptide YY<sub>5</sub> receptor increases food intake in rats. J Biol Chem. 2000 Nov 17;275(46):36043-8.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P1324/cPP1-7-NPY19-23-Ala31-Aib32-Gln34-hPancreatic-Polypeptide-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P1324/cPP1-7-NPY19-23-Ala31-Aib32-Gln34-hPancreatic-Polypeptide-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

313988-89-5

Available Sizes

Curated Selection

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