Pitavastatin (Standard)
Pitavastatin (Standard) is the analytical standard of Pitavastatin. This product is intended for research and analytical applications. Pitavastatin (NK-104) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects[1][2][3][8].
Product Specifications
CAS Number
147511-69-1
UNSPSC
12352100
Target
Apoptosis; Autophagy; HMG-CoA Reductase (HMGCR) ; Mitophagy; Reference Standards
Related Pathways
Apoptosis; Autophagy; Metabolic Enzyme/Protease; Others
Field of Research
Cancer; Metabolic Disease; Neurological Disease; Cardiovascular Disease
Smiles
O=C(O)C[C@H](O)C[C@H](O)/C=C/C1=C(C2=CC=C(F)C=C2)C3=CC=CC=C3N=C1C4CC4
Molecular Formula
C25H24FNO4
Molecular Weight
421.46
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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