BTK degrader-2
BTK degrader-2 (Example 2) is a BTK dual-functional degrading agent, which causes the degradation of BTK through the ubiquitin-proteasome pathway. BTK degrader-2 can be used for the study of B-cell-related diseases[1].
Product Specifications
CAS Number
[2649400-05-3]
UNSPSC
12352005
Target
Btk
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(NC(CC1)=O)[C@@H]1NC(C2=NC=C(N3CCC(CC3)C=O)C=C2)=O
Molecular Formula
C17H20N4O4
Molecular Weight
344.37
References & Citations
[1]Arthur T, et al. Bifunctional compounds for degrading btk via ubiquitin proteosome pathway. WO2021113557A1
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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