EEF1A2-IN-1
EEF1A2-IN-1 is a potent and covalen EEF1A2 inhibitor. EEF1A2-IN-1 exhibits selective antiproliferative activity against osteosarcoma (OS) cells. EEF1A2-IN-1 induces apoptosis by inhibiting EEF1A2 and downregulating the AKT signaling pathway. EEF1A2-IN-1 inhibits tumor growth in a xenograft mouse model. EEF1A2-IN-1 can be used for the research of OS[1].
Product Specifications
UNSPSC
12352005
Target
Akt; Apoptosis
Related Pathways
Apoptosis; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
C=CC(NC(C1=CC=C(C=C1)C2=CC=C(C=C2)O)C(OC)=O)=O
Molecular Formula
C18H17NO4
Molecular Weight
311.33
References & Citations
[1]Xue J, et al. Identification of EEF1A2 as a potential therapy target of osteosarcoma using novel compound 8e. Eur J Med Chem. 2026;302 (Pt 3) :118355.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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