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CBM-4077

CBM-4077 is a PROTAC E3 ligand that can be used for synthesis of PROTACs, such as BCL6-760 (HY-178777) . BCL6-760 is a potent BCL6 PROTAC degrader with anti-tumor activity[1].

Product Specifications

UNSPSC

12352005

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C(C(CC1)C2=NN(C)C3=C2C=CC(NC(CC4)CCN4C5=NC=CC=N5)=C3)NC1=O

Molecular Formula

C22H25N7O2

Molecular Weight

419.48

References & Citations

[1]Shunatona HP, et al. Discovery of Potent and Selective BCL6 Ligand-Directed Degrader (LDD), BCL6-760. J Med Chem. 2025 Oct 23;68 (20) :21502-21519.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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