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TLR7 agonist 33

TLR7 agonist 33 (Compound 141) is a potent TLR7 activator with an EC50 of 1 nM. TLR7 agonist 33 can be used for cancer research[1].

Product Specifications

CAS Number

3099165-43-9

UNSPSC

12352005

Target

Toll-like Receptor (TLR)

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

NC1=NC(N[C@H](CCO)CCC)=C(N(CC2=C(OC)C=CC(CNCC#N)=C2)C3=C4C=CC=C3)C4=N1

Molecular Formula

C27H33N7O2

Molecular Weight

487.60

References & Citations

[1]Sabnis RW. Novel Tricyclic Compounds as TLR7 Agonists for Treating Cancer. ACS Med Chem Lett. 2025 Oct 28;16 (11) :2208-2209.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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