Recombinant GPNMB Monoclonal Antibody
Product Specifications
Background
The protein is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Abbreviation
GPNMB
UniProt
Q14956
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant human GPNMB fragment
Target
UNQ; PRO; GPNMB; HGFIN; NMB; Glycoprotein nmb; Glycoprotein nmb like protein; Osteoactivin; Transmembrane glycoprotein; Transmembrane glycoprotein HGFIN; Transmembrane glycoprotein NMB; UNQ1725; PRO9925; Glycoprotein nmb like protein; Gpnmb; HGFIN; NMB; Osteoactivin; Transmembrane glycoprotein; Transmembrane glycoprotein HGFIN; Transmembrane glycoprotein NMB
Clonality
Monoclonal,Recombinant
Clone
A239
Conjugation
Unconjugated
Applications
WB; IHC; FCM
Field of Research
Immunology; Cancer
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IHC 1:200-1:1000; FCM 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
64 kDa
Observed Molecular Weight
120,95,65 kDa
Isotype
IgG, κ
Available Sizes
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