Tau-aggregation-IN-4
Tau-aggregation-IN-4 is a Tau-aggregation inhibitor (EC50 = 2.99 μM) . Tau-aggregation-IN-4 can be used for the study of neurodegenerative disorders such as Alzheimer’s and Pick’s diseases[1].
Product Specifications
UNSPSC
12352005
Target
Tau Protein
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(C1=CNC2=C1C=CC(NC(CCC3(CCC#C)N=N3)=O)=C2)NC4=CC=CC=C4
Molecular Formula
C23H21N5O2
Molecular Weight
399.45
References & Citations
[1]Conway LP, et al. Discovery of a tau-aggregate clearing compound that covalently targets P4HB. Cell Chem Biol. 2025 Oct 16;32 (10) :1235-1248.e34.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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