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Tau-aggregation-IN-4

Tau-aggregation-IN-4 is a Tau-aggregation inhibitor (EC50 = 2.99 μM) . Tau-aggregation-IN-4 can be used for the study of neurodegenerative disorders such as Alzheimer’s and Pick’s diseases[1].

Product Specifications

UNSPSC

12352005

Target

Tau Protein

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Smiles

O=C(C1=CNC2=C1C=CC(NC(CCC3(CCC#C)N=N3)=O)=C2)NC4=CC=CC=C4

Molecular Formula

C23H21N5O2

Molecular Weight

399.45

References & Citations

[1]Conway LP, et al. Discovery of a tau-aggregate clearing compound that covalently targets P4HB. Cell Chem Biol. 2025 Oct 16;32 (10) :1235-1248.e34.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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