NNRT-IN-14
NNRT-IN-14 is an HIV-1 reverse transcriptase inhibitor (IC50 = 0.175 µM) . NNRT-IN-14 can form hydrogen bonds with LYS101, PRO225, and PHE227, and π–π stacking with TYR181 and TRP229. NNRT-IN-14 can be used for the study of HIV[1].
Product Specifications
UNSPSC
12352005
Target
HIV; Reverse Transcriptase
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
CC1=C(OC2=C(C=NC=C3)C3=NC(NC4=CC=C(C#N)C=N4)=C2)C(C)=CC(/C=C/C#N)=C1
Molecular Formula
C25H18N6O
Molecular Weight
418.45
References & Citations
[1]Baicharoen A, et al. Discovery and molecular docking studies of nitrogen containing naphthyridine derivatives as potent HIV1 NNRTIs with anticancer potential. Sci Rep. 2025 Oct 1;15 (1) :32622.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1
Curated Selection
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