Tafazzin / TAZ Antibody
Product Specifications
Background
This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC) . Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known.
NCBI Gene ID
6901
Swiss Prot
Q16635
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 174-248 of human Tafazzin / TAZ (NP_851830.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
H460
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=14-600
Calculated Molecular Weight
Observed: 50kDa
Fragment
IgG
Applications Notes
WB: 1:1000 - 1:2000
Symbol
TAZ
Positive Control 2
Mouse heart
Positive Control 3
Rat heart
NCBI Official Name
Tafazzin
NCBI Organism
Homo sapiens
Other Product Names
TAZ, tafazzin (cardiomyopathy, dilated 3A (X-linked) endocardial fibroelastosis 2 Barth syndrome), HGNC:11577, BTHS, CMD3A, EFE, EFE2, G4.5, XAP-2, OTTHUMP00000061673, cardiomyopathy, dilated 3A (X-linked), tafazzin
Tested Applications
WB
Physical Properties
Liquid
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