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SARS-CoV-2 Mpro-IN-48

SARS-CoV-2 Mpro-IN-48 is a potent SARS-CoV-2 main protease inhibitor with an IC50 of 21.1 nM. SARS-CoV-2 Mpro-IN-48 exhibits potent antiviral activity against the SARS-CoV-2 JN.1 variant. SARS-CoV-2 Mpro-IN-48 can be used for the research of infection, such as COVID-19[1].

Product Specifications

UNSPSC

12352005

Target

SARS-CoV

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

O=C1N(C2=CC(C)=CN=C2)C(C(C3=CC=C(F)C(Cl)=C3)=C(C4=CC=C(F)C=C4)N1)=O

Molecular Formula

C22H14ClF2N3O2

Molecular Weight

425.82

References & Citations

[1]Rao Z, et al. Discovery and evaluation of pyrimidine-2,4-dione derivatives as novel SARS-CoV-2 Mpro inhibitors with antiviral effect. Bioorg Chem. 2025 Oct;165:109026.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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