VHR-IN-4

VHR-IN-4 (Compound SA7) is a selective vaccinia H1-related (VHR) phosphatase inhibitor with an IC50 of 1.8 μM. VHR-IN-4 can be used for the research of cervical cancer[1].

Product Specifications

CAS Number

[1146616-15-0]

UNSPSC

12352005

Target

Phosphatase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

ClC(C=C1)=CC=C1C2=NN(C3=CC=CC=C3)C=C2/C=C4C(N(C(S/4)=S)CCS(=O)(O)=O)=O

Molecular Formula

C21H16ClN3O4S3

Molecular Weight

506.02

References & Citations

[1]Wu S, et al. Multidentate small-molecule inhibitors of vaccinia H1-related (VHR) phosphatase decrease proliferation of cervix cancer cells. J Med Chem. 2009 Nov 12;52 (21) :6716-23.