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TCO-GK-PEG4-NHS ester

Product Specifications

CAS Number

2307311-19-7

Target

ADC Linker

Related Pathways

Antibody-drug Conjugate/ADC Related

Bioactivity

TCO-GK-PEG4-NHS ester serves as an ADC linker, suitable for synthesizing [18F] AlF-NOTA-Tz-TCO-GK-2Rs15d, which demonstrates high affinity and immunoreactivity to HER2 [1]. This compound is a click chemistry reagent containing a TCO group that can engage in an inverse electron demand Diels-Alder reaction (iEDDA) with Tetrazine-containing molecules.

Smiles

O(C(CCOCCOCCOCCOCCC(NCCCC[C@H](NC(CNC(OC1CCCC=CCC1)=O)=O)C(O)=O)=O)=O)N2C(=O)CCC2=O

Molecular Formula

C33H52N4O14

Molecular Weight

728.78

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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