Factor B-IN-7

Factor B-IN-7 (Compound (I) ) is a selective Factor B inhibitor. Factor B-IN-7 inhibits Factor B-C3b interaction to suppress complement hyperactivation. Factor B-IN-7 is promising for research of paroxysmal nocturnal hemoglobinuria (PNH), C3 glomerulopathy, and age-related macular degeneration (AMD) associated with complement-mediated diseases[1].

Product Specifications

UNSPSC

12352005

Target

Complement System

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology

Smiles

COC1=C(C2=C(C(C)=C1)NC=C2)CN3CCC4(C[C@]35CCC6=C5C=CC(C(O)=O)=C6)CC(F)(C4)F

Molecular Formula

C28H30F2N2O3

Molecular Weight

480.55

References & Citations

[1]Chen JY, et al. Crystal form of multi-membered spiro compound, and preparation method therefor and medical use thereof. WO2025185736A1. 2025-10-02.