IDO1/TDO-IN-9

IDO1/TDO-IN-9 (Compound 66) is a potent dual inhibitor targeting indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO) with IC50s of [1].

Product Specifications

CAS Number

[1878200-88-4]

UNSPSC

12352005

Target

Indoleamine 2,3-Dioxygenase (IDO)

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

99.54

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NC1=NOC2=NC(Cl)=C(F)C=C21

Molecular Formula

C6H3ClFN3O

Molecular Weight

187.56

References & Citations

[1]Brian Desmond Palmer, et al. Inhibitors of tryptophan dioxygenases (ido1 and tdo) and their use in therapy. WO2016024233A1. 2016-02-18.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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