BChE-IN-40
BChE-IN-40 (compound D40) is a potent butyrylcholinesterase inhibitor with an IC50 of 0.59 μM. BChE-IN-40 exhibits strong anti-inflammatory effects with an IC50 of 4.55 μM for nitric oxide suppression. BChE-IN-40 demonstrates excellent blood-brain barrier permeability[1].
Product Specifications
UNSPSC
12352005
Target
Cholinesterase (ChE)
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C1C(OCC2=CC=CC=C2)=C(/C=C/C3=CC=C(OC(N(CC)C)=O)C(OC(N(CC)C)=O)=C3)OC=C1
Molecular Formula
C28H30N2O7
Molecular Weight
506.55
References & Citations
[1]Liu X, et al. A novel carbamate-based hybrid derivative with anti-neuroinflammatory properties as a selective butyrylcholinesterase inhibitor for Alzheimer's disease therapy. Bioorg Chem. 2025 Jul 1;161:108551.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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