Human TRAIL R3 protein, Fc Tag (MALS verified)

Tumor necrosis factor receptor superfamily member 10C (TNFRSF10C) is also known as Decoy receptor 1 (DcR1), TNF-related apoptosis-inducing ligand receptor 3 (TRAIL receptor 3 or TRAIL-R3), CD263. TNFRSF10C is a decoy receptor for TRAIL (tumor necrosis factor-related apoptosis-inducing ligand), a member of the tumor necrosis factor (TNF) ligand family. This receptor is not capable of inducing apoptosis (lacks a cytoplasmic death domain), and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 48.6 kDa. The protein migrates as 65-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Immobilized Human TRAIL R3 protein, Fc Tag (Cat. No. TR3-H52F3) at 5 μg/mL (100 μL/well) can bind Human TRAIL, Mouse IgG2a Fc Tag (Cat. No. TRL-H5259) with a linear range of 1-78 ng/mL (QC tested).