MRT-10350

MRT-10350 (Compound 2) is a cereblon-based HCK molecular glue degrader. MRT-10350 can be used for cancers like chronic myeloid leukemia and HIV-1 infections research[1].

Product Specifications

UNSPSC

12352005

Target

Molecular Glues; Src

Related Pathways

PROTAC; Protein Tyrosine Kinase/RTK

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Smiles

O=C(NC1(C2=CC=C(SC)C=C2)COCC1)NC3=CC4=C(C(N(C(CC5)C(NC5=O)=O)C4)=O)C=C3

Molecular Formula

C25H26N4O5S

Molecular Weight

494.56

References & Citations

[1]Petzold G, et al. Mining the CRBN target space redefines rules for molecular glue-induced neosubstrate recognition. Science. 2025 Jul 3;389 (6755) :eadt6736.