TH16
TH16 is an antibacterial agent (MIC=2 μg/mL against methicillin-resistant Staphylococcus aureus, MRSA) . TH16 disrupts bacterial cytoplasmic membrane integrity, elevating intracellular reactive oxygen species (ROS) levels to induce bacterial death. TH16 is promising for research of bacterial infection[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial; Reactive Oxygen Species (ROS)
Related Pathways
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Infection
Smiles
C=CCC1=CC=C(C(C2=CC=C(C(CC=C)=C2)O)=C1)OC(CCCCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)=O.[Br-]
Molecular Formula
C42H42BrO3P
Molecular Weight
705.66
References & Citations
[1]Feng J, et al. Development of TPP-HK conjugates as membrane-targeting antibacterial agents against methicillin-resistant Staphylococcus aureus. Bioorg Chem. 2025 Aug;163:108758.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-175301/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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