Ilacirnon (Standard)

Ilacirnon (Standard) is the analytical standard of Ilacirnon. This product is intended for research and analytical applications. CCX140 (CCX140-B) is a potent CCR2 antagonist.

Product Specifications

CAS Number

[1100318-47-5]

Product Name Alternative

CCX140 (Standard) ; CCX140-B (Standard)

UNSPSC

12352005

Target

CCR; Reference Standards

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Others

Field of Research

Metabolic Disease; Endocrinology

Smiles

FC(F)(F)C1=CC(S(=O)(NC2=CC(C)=CN=C2C(C3=NC=NC4=C3C=CN4)=O)=O)=CC=C1Cl

Molecular Formula

C20H13ClF3N5O3S

Molecular Weight

495.86

References & Citations

[1]Sullivan T, et al. CCR2 antagonist CCX140-B provides renal and glycemic benefits in diabetic transgenic human CCR2 knockin mice. Am J Physiol Renal Physiol. 2013 Nov 1;305 (9) :F1288-97.|[2]Sullivan TJ, et al. Experimental evidence for the use of CCR2 antagonists in the treatment of type 2 diabetes. Metabolism. 2013 Nov;62 (11) :1623-32.