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(S, R, S) -AHPC-Me-amide-C15-acid

(S, R, S) -AHPC-Me-amide-C15-acid is a synthesized E3 ligase ligand-linker conjugate that can be used for synthesis of PROTACs such as C199 (HY-174445) [1].

Product Specifications

UNSPSC

12352100

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C(N[C@H](C1=CC=C(C=C1)C2=C(N=CS2)C)C)[C@H]3N(C[C@@H](C3)O)C([C@H](C(C)(C)C)NC(CCCCCCCCCCCCCCCC(O)=O)=O)=O

Molecular Formula

C40H62N4O6S

Molecular Weight

727.01

References & Citations

[1]Yong Ju, et al. Development of a Selective and Potent PRMT4 PROTAC Degrader with Efficacy against Multiple Myeloma in Vitro and in Vivo. J Med Chem. 2025 Jul 10. 68 (13) : 13973-13989.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Von Hippel-Lindau (VHL)

Curated Selection

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