Recombinant SMARCA2/BRM Monoclonal Antibody
Product Specifications
Background
SMARCA2, also named as BRM, is a transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. SMARCA2 is involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.
Abbreviation
SMARCA2/BRM
UniProt
P51531
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human SMARCA2/BRM fragment
Target
SNF2L; SMARCA; BAF190B; BRM; SNF2A; SNF2L2; SMARCA2; ATP dependent helicase SMARCA2; ATP-dependent helicase SMARCA2; BAF190; BRG1-associated factor 190B; FLJ36757; Global transcription activator homologous sequence; hBRM; hSNF2a; MGC74511; Possible global transcription activator SNF2L2; Probable global transcription activator SNF2L2; Protein brahma homolog; SMCA2; SNF2 alpha; SNF2 like 2; SNF2/SWI2 like protein 2; SNF2-alpha; SNF2LA; Sth1p; Sucrose nonfermenting 2 like protein 2; SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2
Clonality
Monoclonal,Recombinant
Clone
A624
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000; IHC 1:500-1:3000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product MSDS
https://789.bio/eb/ZXB80oB5
Calculated Molecular Weight
181 kDa
Observed Molecular Weight
220 kDa
Isotype
IgG, κ
Available Sizes
Curated Selection
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