Thalidomide-NH-alkynes
Thalidomide-NH-alkynes is a synthesized E3 ligase ligand-linker conjugate that can be used for synthesis of PROTAC HDAC degrader-2 (HY-174444) [1].
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
C#CCCCCOC(CNC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O)=O
Molecular Formula
C21H21N3O6
Molecular Weight
411.41
References & Citations
[1]Zhai S, et al. Development and Characterization of the First Selective Class IIb Histone Deacetylase Degraders. J Med Chem. 2025 Jul 10;68 (13) :13793-13821.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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