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TMTHSI succinimide NHS ester

TMTHSI succinimide NHS ester is a highly efficient cyclic alkyne click reagent. TMTHSI succinimide NHS ester has the primary activity to rapidly undergo strain-promoted cycloaddition reactions with azides. TMTHSI succinimide NHS ester is easily functionalized and can be linked to a variety of small molecules and (peptides, nucleic acids) biologics via a variety of linkers[1].

Product Specifications

CAS Number

[2408481-83-2]

UNSPSC

12352005

Target

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Smiles

O=C(CCC(ON1C(CCC1=O)=O)=O)N=S2(CC(C)(C)C#CC(C)(C2)C)=O

Molecular Formula

C18H24N2O6S

Molecular Weight

396.46

References & Citations

[1]Weterings J, et al. TMTHSI, a superior 7-membered ring alkyne containing reagent for strain-promoted azide-alkyne cycloaddition reactions. Chem Sci. 2020 Aug 10;11 (33) :9011-9016.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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