Gly-PEG3-endo-BCN
Product Specifications
UNSPSC Description
Gly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Gly-PEG3-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gly-peg3-endo-bcn.html
Solubility
10 mM in DMSO
Smiles
O=C(OCC1[C@@]2([H])CCC#CCC[C@@]12[H])NCCCOCCOCCOCCCNC(CN)=O
Molecular Weight
453.57
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-140080/Gly-PEG3-endo-BCN-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-140080/
Clinical Information
No Development Reported
CAS Number
2354291-37-3
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