SHP2-IN-41

SHP2-IN-41 (Compound 4) is a SHP2 inhibitor with an IC50 of less than 0.1 μM. SHP2-IN-41 has an IC50 against KYSE-520 cells also less than 0.1 μM. SHP2-IN-41 can be used in the study of cancer[1].

Product Specifications

CAS Number

[3081261-84-6]

UNSPSC

12352100

Target

SHP2

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

N[C@@H]1C2=C(CC13CCN(CC3)C4=NC=C(N=C4)SC5=CC6=C(B(OC6)O)C=C5Cl)C=CC=C2

Molecular Formula

C24H24BClN4O2S

Molecular Weight

478.80

References & Citations

[1]Ninghui YU, et al. Benzo [c] [1, 2] oxaborol-1 (3h) -ol derivatives as shp2 inhibitors, compositions and methods thereof. WO2025081291A1. 2025-04-24.