ChX710
ChX710 could prime the type I interferon response to cytosolic DNA, which induces the ISRE promoter sequence, specific cellular Interferon-Stimulated Genes (ISGs), and the phosphorylation of Interferon Regulatory Factor (IRF) 3.
Product Specifications
CAS Number
[2438721-44-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ChX710.html
Purity
99.91
Solubility
DMSO : 20 mg/mL (ultrasonic)
Smiles
O=C(NC(C)CN(C)C)C1=C(N=C(C2=CC=NC=C2)N3)C3=CC=C1
Molecular Formula
C18H21N5O
Molecular Weight
323.39
Precautions
H302, H315, H319, H335
References & Citations
[1]Khiar S, et al. Identification of a small molecule that primes the type I interferon response to cytosolic DNA. Sci Rep. 2017 May 31;7 (1) :2561.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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