Sigma-2 Receptor ligand 1
Sigma-2 Receptor ligand 1 (Compound 7i) is a highly selective Sigma-2 receptor ligand with a Ki value of 40 nM. Sigma-2 Receptor ligand 1 is promising for research of Alzheimer's disease[1].
Product Specifications
UNSPSC
12352005
Target
Sigma Receptor
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
C12=CC=CC=C1C(CCN3C4C5CC(C3)C[C@@H]4C6CCOCC6)=C5N2
Molecular Formula
C22H28N2O
Molecular Weight
336.47
References & Citations
[1]Hughes AJ, et al. Discovery of Iboga-Derived Ligands for the Sigma‑2 Receptor. ACS Bio Med Chem Au. 2025 May 12;5 (3) :379-386.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Sigma 2 Receptor
Curated Selection
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