CD20/MS4A1 Monoclonal Antibody
Product Specifications
Background
CD20 is a 297 amino acid (aa) non-glycosylated type III membrane protein that is the founding member of the MS4A tetraspanin protein family. It is expressed on pre-B, naïve and mature B lymphocytes and B-cell lymphomas. CD20 is associated with lipid rafts upon crosslinking, and appears to play a role in regulation of ion influx. The one extracellular segment of 48 aa shows 65% aa sequence identity between human and mouse CD20.
Abbreviation
MS4A1
UniProt
P11836
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD20/MS4A1 Protein
Target
LEU; CVID; B-lymphocyte antigen CD; Leukocyte surface antigen Leu; B-lymphocyte surface antigen B; Membrane-spanning 4-domains subfamily A member; MS4A1; B1; Bp35; CD20; CVID5; LEU-16; MS4A2; S7; B-lymphocyte antigen CD20; B-lymphocyte surface antigen B1; Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; Bp35; Ly-44; APY; ATOPY; B lymphocyte antigen CD20; B Lymphocyte Cell Surface Antigen B1; B-lymphocyte cell-surface antigen B1; Bp 35; CD 20; CD20 antigen; CD20 receptor; Fc epsilon receptor I beta chain; Fc Fragment of IgE high affinity I receptor for beta polypeptide; FCER1B; High affinity immunoglobulin epsilon receptor subunit beta; IgE Fc receptor subunit beta; IGEL; IGER; IGHER; LEU 16; LEU16; leukocyte surface antigen Leu 16; Ly44; Membrane spanning 4 domains A1; Membrane spanning 4 domains subfamily A member 2; MGC3969
Clonality
Monoclonal
Clone
12G5
Conjugation
Unconjugated
Applications
WB; IHC-P; IP
Field of Research
Immunology; Stem Cells; Cancer
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC-P 1:100-1:1000; IP 1-5 μL/mg of lysate
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Product MSDS
https://789.bio/eb/ZCXdpQGY
Calculated Molecular Weight
33 kDa
Observed Molecular Weight
36 kDa
Isotype
IgG1
Curated Selection
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