DB-10
DB-10 is a pro-agent of 3-nbutylphthalide (NBP) (HY-B0647) . DB-10 has significantly high uptake ability via pyrilamine cationic transporters in the temperature and energy dependent manner in cells. DB-10 improves the survival rate of cells. DB-10 could rapidly convert into active original agent and increase the accumulation in the brain in vivo. DB-10 can be used for ischemic stroke study[1].
Product Specifications
UNSPSC
12352005
Target
P38 MAPK
Related Pathways
MAPK/ERK Pathway
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C(NCCN(C)C)C1=CC=CC=C1C(O)CCCC
Molecular Formula
C16H26N2O2
Molecular Weight
278.39
References & Citations
[1]Han Y, et al. A brain-targeting dl-3-n-butylphthalide prodrug to treat ischemic stroke. Eur J Med Chem. 2025 Jun 5;290:117474.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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