HSP90α-IN-1
HSP90α-IN-1 is a HSP90α inhibitor (IC50 = 111 nM) that exhibits senolytic activity across various cellular senescence models. HSP90α-IN-1 is related to the xanthinic family. HSP90α-IN-1 is involved in research on combating age-related inflammaging and diseases, including cancer, and possibly extend a healthy lifespan[1].
Product Specifications
CAS Number
[184897-90-3]
UNSPSC
12352005
Target
HSP; Interleukin Related
Related Pathways
Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(N1CC2=CC=CC=C2)N(C3=CC=CC=C3C)C4=C(NC=N4)C1=O
Molecular Formula
C19H16N4O2
Molecular Weight
332.36
References & Citations
[1]Atlante S, et al., A Xanthine Derivative With Novel Heat Shock Protein 90-Alpha Inhibitory and Senolytic Properties. Aging Cell. 2025 Mar 17:e70047.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HSP90
Curated Selection
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