Soclenicant
Soclenicant (BNC210) is an orally active α7 nAChR negative alteration modulator (NAM) with no apparent side effects. Soclenicant exhibits acute anxiolytic activity in rodent models of anxiety. Soclenicant inhibits rat and human α7 nAChR currents (in stably transfected cell lines) induced by acetylcholine, nicotine, choline, and the a7-specific agonist PNU-282987 with IC50 values in the range of 1.2 to 3 μM. Soclenicant can be used in studies of anxiety, trauma, and stressor-related disorders[1][2][3][4].
Product Specifications
CAS Number
1020634-41-6
Product Name Alternative
BNC210; IW-2143
UNSPSC
12352005
Target
NAChR
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
99.75
Solubility
DMSO : 10 mg/mL (ultrasonic)
Smiles
O=C1C2=CC(NC3CC4=C(C3)C=CC=C4)=CN=C2N(CC)C=C1C(N5CCOCC5)=O
Molecular Formula
C24H26N4O3
Molecular Weight
418.49
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
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