CENPJ Antibody
Product Specifications
Background
This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation. Alternatively spliced transcript variants have been found for this gene.
NCBI Gene ID
55835
Swiss Prot
Q9HC77
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1069-1338 of human CENPJ (NP_060921.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
Raji
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 153kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
CENPJ
NCBI Official Name
Centromere protein J
NCBI Organism
Homo sapiens
Other Product Names
BM032, CENP-J, CPAP, LAP, LIP1, MCPH6, SASS4, SCKL4, Sas-4, centromere protein J, LAG-3-associated protein, LYST-interacting protein 1, LYST-interacting protein LIP1, LYST-interacting protein LIP7, Spindle assembly abnormal 4, centrosomal P4.1-associated protein
Tested Applications
WB
Physical Properties
Liquid
Frequently Asked Questions
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