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HER2-IN-21

HER2-IN-21 (compound 657994) is a human epidermal growth factor receptor 2 (HER2) inhibitor, with an IC50 of 3.85 μM[1].

Product Specifications

CAS Number

906437-59-0

UNSPSC

12352005

Target

EGFR

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

COC1=CC=CC(C2SC(N)=NC3=C2C(C)=NN3C(C4=CC=CC=C4O)=O)=C1

Molecular Formula

C20H18N4O3S

Molecular Weight

394.45

References & Citations

[1]Matrouk AY, et al. Discovery of New HER2 Inhibitors via Computational Docking, Pharmacophore Modeling, and Machine Learning. Mol Inform. 2025 Feb;44 (2) :e202400336.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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