HER2-IN-21
HER2-IN-21 (compound 657994) is a human epidermal growth factor receptor 2 (HER2) inhibitor, with an IC50 of 3.85 μM[1].
Product Specifications
CAS Number
[906437-59-0]
UNSPSC
12352005
Target
EGFR
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
COC1=CC=CC(C2SC(N)=NC3=C2C(C)=NN3C(C4=CC=CC=C4O)=O)=C1
Molecular Formula
C20H18N4O3S
Molecular Weight
394.45
References & Citations
[1]Matrouk AY, et al. Discovery of New HER2 Inhibitors via Computational Docking, Pharmacophore Modeling, and Machine Learning. Mol Inform. 2025 Feb;44 (2) :e202400336.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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