IBFAR2
IBFAR2, a BFAR inhibitor, restores the CD8+ TRM cell subset against solid tumors. iBFAR2 promotes JAK2-STAT1 association and STAT1 phosphorylation[1].
Product Specifications
CAS Number
353484-02-3
UNSPSC
12352005
Target
JAK; STAT
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
FC(F)(F)C1=CC=CC2=C1NC(C3=CC=C([N+]([O-])=O)C=C3)C4C2C=CC4
Molecular Formula
C19H15F3N2O2
Molecular Weight
360.33
References & Citations
[1]Siyu Pei, et al. Age-related decline in CD8+ tissue resident memory T cells compromises antitumor immunity. Nat Aging. 2024 Dec;4 (12) :1828-1844.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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