RET ligand-1
RET ligand-1 is a target protein ligand targeting RET that can be used to synthesize PROTAC LDD39 (HY-159967) [1].
Product Specifications
CAS Number
[3028787-16-5]
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC; RET
Related Pathways
PROTAC; Protein Tyrosine Kinase/RTK
Field of Research
Others
Smiles
CCOC1=CN2N=CC(C#N)=C2C(C3=CN=C(N4CCC(C=O)(CC4)NC(C5=C(F)C=CC(F)=C5)=O)C=C3)=C1
Molecular Formula
C28H24F2N6O3
Molecular Weight
530.53
References & Citations
[1]Qiao JX, et al. Discovery and Synthesis of Heterobifunctional Degraders of Rearranged during Transfection (RET) Kinase. J Med Chem. 2024 Nov 14;67 (21) :19736-19754.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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