NSC 645827
NSC 645827 is an inhibitor for NAD (P) H: quinone oxidoreductase 1 (NQO1) with an IC50 of 0.7 μM[1].
Product Specifications
CAS Number
[128113-19-9]
UNSPSC
12352005
Target
Quinone Reductase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=C1C2=CC(O)=CC=C2N3N=NC4=C3C1=C(NCCN(C)C)C=C4
Molecular Formula
C17H17N5O2
Molecular Weight
323.35
References & Citations
[1]Jianwen Wang, et al. Identification and structure-guided development of triazole urea-based selective antagonists of Arabidopsis karrikin signaling. Nat Commun. 2025 Jan 2;16 (1) :104.|[2]Chee S M. Design, Synthesis and Biological Evaluation of the Novel Inhibitors of Enzymes NQO1 and NQO2[M]. The University of Manchester (United Kingdom), 2014.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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