Vaccarin C
Vaccarin C (Compound VIII) is a cycloheptapeptide with good antifungal activity against pathogenic fungi and dermatophytes M. audouinii and T. mentagrophytes with MIC values of 6 µg/mL. Vaccarin C also has high cytotoxicity against Dalton's lymphoma ascites (DLA) and Ehrlich's ascites carcinoma (EAC) cell lines with IC50 values of 3.35 and 5.72 μM, respectively[1].
Product Specifications
CAS Number
177602-12-9
UNSPSC
12352209
Target
Fungal
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Smiles
O=C(N1[C@@](C(NCC(N[C@H](C(N[C@H](C(N2[C@](CCC2)([H])C(N[C@H](C(N3)=O)CC(C)C)=O)=O)C(C)C)=O)CC4=CC=C(C=C4)O)=O)=O)([H])CCC1)[C@@H]3CC5=CNC6=CC=CC=C56
Molecular Formula
C43H56N8O8
Molecular Weight
812.95
References & Citations
[1]Dahiya R, et al. Synthesis and pharmacological investigation of segetalin C as a novel antifungal and cytotoxic agent. Arzneimittelforschung. 2008;58 (1) :29-34.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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