SDH-IN-12
Product Specifications
UNSPSC Description
SDH-IN-12 (compound 9b) is a succinate dehydrogenase inhibitor, which exhibits activity against S. sclerotiorum and C. arachidicola, with EC50s of 0.97 and 2.07 μM, respectively. SDH-IN-12 reveals no significant herbicidal activity against monocotyledonous and dicotyledonous plants[1].
Target Antigen
Fungal; Succinate Dehydrogenase
Type
Reference compound
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sdh-in-12.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=C(C2=CC(F)=C(F)C(F)=C2)C=CC=C1)NC(C3=CN(C)N=C3C(F)F)=O
Molecular Weight
424.32
References & Citations
[1]Sun NB, et al., Novel Pyrazole Acyl(thio)urea Derivatives Containing a Biphenyl Scaffold as Potential Succinate Dehydrogenase Inhibitors: Design, Synthesis, Fungicidal Activity, and SAR. J Agric Food Chem. 2024 Feb 7;72(5):2512-2525.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163284/SDH-IN-12-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163284/
Clinical Information
Phase 1
CAS Number
3027210-28-9
Curated Selection
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