Vaccarin C

Vaccarin C (Compound VIII) is a cycloheptapeptide with good antifungal activity against pathogenic fungi and dermatophytes M. audouinii and T. mentagrophytes with MIC values of 6 µg/mL. Vaccarin C also has high cytotoxicity against Dalton's lymphoma ascites (DLA) and Ehrlich's ascites carcinoma (EAC) cell lines with IC50 values of 3.35 and 5.72 μM, respectively[1].

Product Specifications

CAS Number

[177602-12-9]

UNSPSC

12352209

Target

Fungal

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Smiles

O=C(N1[C@@](C(NCC(N[C@H](C(N[C@H](C(N2[C@](CCC2)([H])C(N[C@H](C(N3)=O)CC(C)C)=O)=O)C(C)C)=O)CC4=CC=C(C=C4)O)=O)=O)([H])CCC1)[C@@H]3CC5=CNC6=CC=CC=C56

Molecular Formula

C43H56N8O8

Molecular Weight

812.95

References & Citations

[1]Dahiya R, et al. Synthesis and pharmacological investigation of segetalin C as a novel antifungal and cytotoxic agent. Arzneimittelforschung. 2008;58 (1) :29-34.