Delgocitinib (ethanolate)
Product Specifications
UNSPSC Description
Delgocitinib ethanolate is a specific JAK inhibitor with IC50s of 2.8, 2.6, 13 and 58 nM for JAK1, JAK2, JAK3 and Tyk2, respectively[1].
Target Antigen
JAK
Type
Reference compound
Related Pathways
Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/delgocitinib-ethanolate.html
Smiles
CCO.N#CCC(N1[C@]2([C@H](C1)C)CN(C3=C4C(NC=C4)=NC=N3)CC2)=O
Molecular Weight
356.42
References & Citations
[1]Tanimoto A, et al. Pharmacological properties of JTE-052: a novel potent JAK inhibitor that suppresses various inflammatory responses in vitro and in vivo. Inflamm Res. 2015 Jan;64(1):41-51.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-109053A/Delgocitinib-ethanolate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-109053A/
Clinical Information
Phase 3
CAS Number
2064338-33-4
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