Indisulam analog-1
Indisulam analog-1 (Compound 4) is an analog of Indisulam (HY-13650) . Indisulam analog-1 recruits DCAF15-DDB1-DDA1-RBM39 with an EC50 of 1.21 µM. Indisulam analog-1 can be used in the research of colon cancer[1].
Product Specifications
CAS Number
[444579-59-3]
UNSPSC
12352005
Target
Molecular Glues
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
N#CC1=CNC2=C1C=CC=C2NS(=O)(C3=CC=C(S(=O)(N)=O)C=C3)=O
Molecular Formula
C15H12N4O4S2
Molecular Weight
376.41
References & Citations
[1]Bussiere DE, et al. Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex. Nat Chem Biol. 2020 Jan;16 (1) :15-23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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