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Indisulam analog-1

Indisulam analog-1 (Compound 4) is an analog of Indisulam. Indisulam analog-1 recruits DCAF15-DDB1-DDA1-RBM39 with an EC50 of 1.21 µM. Indisulam analog-1 can be used in the research of colon cancer[1].

Product Specifications

CAS Number

444579-59-3

UNSPSC

12352005

Target

Molecular Glues

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

N#CC1=CNC2=C1C=CC=C2NS(=O)(C3=CC=C(S(=O)(N)=O)C=C3)=O

Molecular Formula

C15H12N4O4S2

Molecular Weight

376.41

References & Citations

[1]Bussiere DE, et al. Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex. Nat Chem Biol. 2020 Jan;16 (1) :15-23.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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