Dihydrotetrabenazine
Dihydrotetrabenazine (DHTBZ) is the active metabolite of Tetrabenazine (HY-B0590) . Dihydrotetrabenazine is the inhibitor for human vesicular monoamine transporter 2 (VMAT2), that reduces monoamine content in presynaptic neurons, and can be used in movement disorder research[1].
Product Specifications
CAS Number
[3466-75-9]
Product Name Alternative
DHTBZ
UNSPSC
12352005
Hazard Statement
H302
Target
Monoamine Transporter
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Neurological Disease
Purity
99.23
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
OC1C(CC(C)C)CN2CCC3=CC(OC)=C(OC)C=C3C2C1
Molecular Formula
C19H29NO3
Molecular Weight
319.44
Precautions
H302
References & Citations
[1]Chen JJ, et al., Tetrabenazine for the treatment of hyperkinetic movement disorders: a review of the literature. Clin Ther. 2012 Jul;34 (7) :1487-504.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Curated Selection
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